Reprogramming liver-stem WB cells into functional insulin-producing cells by persistent expression of Pdx1- and Pdx1-VP16 mediated by lentiviral vectors

This publication has 31 references indexed in Scilit:

• Constitutively active PDX1 induced efficient insulin production in adult murine liver
  Biochemical and Biophysical Research Communications, 2005
• Functional, Persistent, and Extended Liver to Pancreas Transdifferentiation
  Journal of Biological Chemistry, 2003
• Experimental Conversion of Liver to Pancreas
  Current Biology, 2003
• In vitro differentiation of WB-F344 rat liver epithelial cells into the biliary lineage
  Differentiation, 2002
• Efficacy and safety analyses of a recombinant human immunodeficiency virus type 1 derived vector system
  Gene Therapy, 1999
• Pancreatic agenesis attributable to a single nucleotide deletion in the human IPF1 gene coding sequence
  Nature Genetics, 1997
• Adenovirus-Mediated Hepatic Gene Transfer in Mice: Comparison of Intravascular and Biliary Administration
  Human Gene Therapy, 1996
• Hematopoietic stem cell markers are expressed by ductal plate and bile duct cells in developing human liver
  Hepatology, 1995
• GAL4-VP16 is an unusually potent transcriptional activator
  Nature, 1988
• Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression.
  Genes & Development, 1988