LIPOIDS AND LIPOID DISEASES
- 1 March 1934
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of internal medicine (1908)
- Vol. 53 (3) , 379-390
- https://doi.org/10.1001/archinte.1934.00160090056005
Abstract
The clinical syndrome known variously as Schüller-Christian's disease, Christian's syndrome, xanthomatosis of the skeletal type and dysostosis hypophysaria and also described as "defects in membranous bones, exophthalmos and diabetes insipidus" was first described by Hand1in 1893. Hand presented the case of a 3 year old boy with exophthalmos and polyuria in whom autopsy revealed a soft, movable yellow spot about the size of a five cent piece, involving the entire thickness of the skull in the right parietal region. In 1916, Schüller2reported two cases, one in a boy of 16 with dystrophia adiposogenitalis, exophthalmos and marked cranial defects and the other in a girl of 4 years with polyuria, exophthalmos and defects of the skull. Schüller felt that both cases were examples of skeletal defects secondary to disease of the hypophysis. Christian,3in 1919, reported a case of defects in the membranous bones, exophthalmos andThis publication has 0 references indexed in Scilit: