A Randomized Trial of Postoperative Five-Versus Three-Drug Chemotherapy After Mastectomy: A Cancer and Leukemia Group B (CALGB) Study
- 1 January 1982
- book chapter
- Published by Springer Nature
- Vol. 80, 170-176
- https://doi.org/10.1007/978-3-642-81685-7_28
Abstract
The Cancer and Leukemia Group B (CALB) has conducted a randomized study of adjuvant chemotherapy in patients with breast cancer who have involved axillary nodes at the time of mastectomy. Five-drug treatment (CMFVP) was compared with three-drug treatment (CMF). For patients with more than three involved nodes, the CMFVP regimen produced a significantly prolonged disease-free survival in comparison to the CMF regimen.Keywords
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