Requirement for Homologous Recombination Functions for Expression of the mutA Mistranslator tRNA-Induced Mutator Phenotype in Escherichia coli
Open Access
- 1 March 2000
- journal article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 182 (5) , 1427-1431
- https://doi.org/10.1128/jb.182.5.1427-1431.2000
Abstract
Expression of the Escherichia coli mutA mutator phenotype requires recA, recB,recC, ruvA, and ruvC gene, but notrecD, recF, recO, orrecR genes. Thus, the recBCD-dependent homologous recombination system is a component of the signal pathway that activates an error-prone DNA polymerase inmutA cells.Keywords
This publication has 44 references indexed in Scilit:
- Mutator tRNAs are encoded by the Escherichia coli mutator genes mutA and mutC: a novel pathway for mutagenesis.Proceedings of the National Academy of Sciences, 1996
- Involvement of RecF pathway recombination genes in postreplication repair in UV-irradiated Escherichia coli cellsMutation Research/DNA Repair, 1994
- UV irradiation of Escherichia coli modulates mutagenesis at a site-specific ethenocytosine residue on M13 DNA. Evidence for an inducible recA-independent effectBiochemistry, 1993
- Quantitative multiplex sequence analysis of mutational hot spots. Frequency and specificity of mutations induced by a site-specific ethenocytosine in M13 viral DNABiochemistry, 1993
- Mechanisms of mutagenesis by exocyclic DNA adducts. Transfection of M13 viral DNA bearing a site-specific adduct shows that ethenocytosine is a highly efficient RecA-independent mutagenic noninstructional lesionBiochemistry, 1991
- mutA and mutC: two mutator loci in Escherichia coli that stimulate transversions.Proceedings of the National Academy of Sciences, 1990
- Genetic Analysis of Conjugational Recombination in Escherichia coli K12 Strains Deficient in RecBCD EnzymeMicrobiology, 1987
- Chi-dependent DNA strand cleavage by RecBC enzymeCell, 1985
- Genetic analysis and molecular cloning of the Escherichia coli ruv geneMolecular Genetics and Genomics, 1984
- The lexA gene product represses its own promoter.Proceedings of the National Academy of Sciences, 1980