Cigarette smoke affects lipolytic activity in isolated rat lungs
- 1 July 1980
- Vol. 15 (7) , 539-543
- https://doi.org/10.1007/bf02534227
Abstract
Isolated perfused rat lungs liberated fatty acids at a rate of 15 μmol/hr during perfusion of triglyceride-rich medium through the pulmonary vascular bed. About 80% of this activity seemed to result from lipoprotein lipase and 20% to hormone-sensitive lipase. Ventilation of the lungs with cigarette smoke instead of air during the perfusion reduced fatty acid liberation by 23%. Pre-exposure of rats to cigarette smoke for either 1 or 10 days did not cause significant changes in lung lipolytic activity compared to sham-exposed controls.Keywords
This publication has 28 references indexed in Scilit:
- HIGH-DENSITY LIPOPROTEIN MAY NOT BE ANTIATHEROGENIC AFTER ALLThe Lancet, 1979
- HIGH-DENSITY LIPOPROTEIN AND CORONARY RISK FACTORS IN NORMAL MENThe Lancet, 1979
- The effects of cigarette smoke exposure on testosterone metabolism in the isolated perfused rat lungThe Journal of Steroid Biochemistry and Molecular Biology, 1978
- Lipoprotein lipase in rat lung effect of dexamethasoneBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1976
- Metabolism of testosterone in the isolated perfused rat lungsJournal of Steroid Biochemistry, 1976
- Lipoprotein lipase in rat lung the effect of fastingBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1975
- PLASMA-HIGH-DENSITY-LIPOPROTEIN CONCENTRATION AND DEVELOPMENT OF ISCHÆMIC HEART-DISEASEThe Lancet, 1975
- Inhibition of Lipase Activity of Lung and Adipose Tissue by Phenothiazine DerivativesNature, 1964
- TISSUE DISTRIBUTION OF C14 AFTER THE INTRAVENOUS INJECTION OF LABELED CHYLOMICRONS AND UNESTERIFIED FATTY ACIDS IN THE RATJournal of Clinical Investigation, 1958
- Die Fettspaltung durch Lungengewebe.Hoppe-Seyler´s Zeitschrift Für Physiologische Chemie, 1908