DEMETHYLATION IN RATS CHRONICALLY TREATED WITH COCAINE

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  • 1 January 1976
    • journal article
    • letter
    • Vol. 13  (3) , 555-558
Abstract
Norcocaine was prepared from cocaine utilizing diethyl azodicarboxylate. The rate of demethylation of 14C-cocaine in rats receiving either chronic or acute dosages of the drug was investigated. No significant difference in the rate of 14CO2 exhalation from the 2 groups was observed.

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