Lipophilicity of acceptor substrate as a factor in “late foetal” rat liver microsomal UDP-glucuronosyltransferase activity
- 1 April 1980
- journal article
- research article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 29 (7) , 999-1006
- https://doi.org/10.1016/0006-2952(80)90162-8
Abstract
No abstract availableThis publication has 26 references indexed in Scilit:
- Demonstration of two functionally heterogenous groups within the activities of UDP-glucuronosyltransferase towards a series of 4-alkyl-substituted phenolsBiochemical Journal, 1979
- Demonstration of functional heterogeneity of hepatic uridine diphosphate glucuronosyltransferase activities after administration of 3-methylcholanthrene and phenobarbital to ratsBiochemical Journal, 1978
- Functional heterogeneity of UDP-glucuronosyltransferase as indicated by its differential development and inducibility by glucocorticoids. Demonstration of two groups within the enzyme's activity towards twelve substratesBiochemical Journal, 1978
- The role of substrate lipophilicity in determining type 1 microsomal P450 binding characteristicsBiochemical Pharmacology, 1978
- Ks values of some homologous series of barbiturates and the relationship with the lipophilicity and metabolic clearanceBiochemical Pharmacology, 1977
- Steroid and non-steroid UDP glucuronyltransferase: Glucuronidation of synthetic estrogens as steroidsThe Journal of Steroid Biochemistry and Molecular Biology, 1977
- Observations on the accessibility of acceptor substrates to the active centre of UDP-glucuronosyltransferase in vitroBiochimica et Biophysica Acta (BBA) - Enzymology, 1976
- The dealkylation of some p-nitrophenylalkylethers and their α-deuterated analogues by rat liver microsomesBiochemical Pharmacology, 1975
- Selection of a Reference Partitioning System for Drug Design WorkJournal of Pharmaceutical Sciences, 1975
- Influence of Hydrophobic Character on the Relative Rate of Oxidation of Drugs by Rat Liver MicrosomesJournal of Medicinal Chemistry, 1971