Effect of size of food on food consumption: Some neurophysiological considerations.

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Abstract
Reports results of 3 experiments with 42 B6D2F1/J mice and 3 groups of 2 CAF1/J, C3D2F1/J, and LAF1/J mice. Ss that normally ate about 3.4 g of food in a 24-hr period increased food consumption 20% when offered their food in the form of 2 7.5-g pellets. This effect disappeared when Ss were offered 2 5.0-g pellets instead, or random-sized pellets. This finding indicates that the presence of large food pellets potentiates food intake in normal mice. Blinding disrupted this food-size-food-intake phenomenon. Lateral hypothalamic lesions disrupted the overeating under large pellet conditions, while both ventromedial hypothalamic and septal lesions affected eating of small pellets. Septal lesions increased consumption of small pellets, while ventromedial hypothalamic lesions reduced the intake of small pellets. (22 ref) (PsycINFO Database Record (c) 2006 APA, all rights reserved)

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