Melatonin: Identification of Sites of Antigonadal Action in Mouse Brain
- 13 November 1981
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 214 (4522) , 821-823
- https://doi.org/10.1126/science.7292016
Abstract
Long-term implants releasing a small quantity of melatonin (45 nanograms per day) were used to determine the brain sites of the hormone's antigonadal action in a photoperiodic species, the white-footed mouse ( Peromyscus leucopus ). Implants in the medial preoptic and supra- and retrochiasmatic areas elicited complete gonadal regression after 7 weeks. Implants in other brain regions had little effect on the animals' reproductive state.This publication has 32 references indexed in Scilit:
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