Epidermal growth factor receptor activity and clinical outcome in glioblastoma and meningioma
- 1 January 1993
- journal article
- research article
- Published by Taylor & Francis in British Journal Of Neurosurgery
- Vol. 7 (2) , 197-199
- https://doi.org/10.3109/02688699309103479
Abstract
Epidermal growth factor receptor (EGF-r) activity in patients with glioblastoma multiforme (GBM: n = 27) and meningioma (n = 18) was compared with clinical outcome. All patients with GBM were followed up to time of death. In patients with GBM there was no significant relationship between EGF-r activity and either patient survival time or age. EGF-r activity in patients with meningioma was neither related to age nor, at a median of 40 months after surgery, to clinical outcome. These results suggest that routine estimation of EGF-r activity in these intracranial tumours is not indicated.Keywords
This publication has 7 references indexed in Scilit:
- Epidermal growth factor receptors in intracranial and breast tumours: their clinical significanceBritish Journal of Cancer, 1991
- Prognostic factors for high-grade malignant glioma: Development of a prognostic indexJournal of Neuro-Oncology, 1990
- Investigation of the expression of epidermal growth factor receptor and blood group A antigen in 110 human gliomasNeuropathology and Applied Neurobiology, 1990
- Proto-oncogene abnormalities and their relationship to tumorigenicity in some human glioblastomasJournal of Neurosurgery, 1989
- Enhancement of Growth of Primary Metastatic Fresh Human Tumors of the Nervous System by Epidermal Growth Factor in Serum-free Short Term CultureNeurosurgery, 1988
- Growth effects of epidermal growth factor (EGF) and a monoclonal antibody against the EGF receptor on four glioma cell linesActa Neuropathologica, 1988
- THE RECURRENCE OF INTRACRANIAL MENINGIOMAS AFTER SURGICAL TREATMENTJournal of Neurology, Neurosurgery & Psychiatry, 1957