Association between salt sensitivity and insulin concentrations in patients with hypertension*

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Abstract
This study was performed in 28 patients with mild to moderate hypertension, classified as being either salt sensitive or salt resistant on the basis of the percent decrement in mean arterial blood pressure (MAP) seen 7 days after daily salt intake was decreased from 220 to 30 mmol/L. Ten patients had a percent decrease of MAP >10% and were defined as being salt sensitive. Salt resistance was defined as a percent decrease in MAP of P < .10) and insulin (r = 0.38, P < .06) responses to oral glucose. These data are consistent with the view that there is an association between resistance to insulin-mediated glucose disposal and salt sensitivity in patients with high blood pressure. Am J Hypertens 1995;8:855–858

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