Immune mechanisms in leukemia role of the Ia antigens.
Open Access
- 1 April 1977
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 145 (4) , 1077-1081
- https://doi.org/10.1084/jem.145.4.1077
Abstract
We have shown that the selective removal of cells possessing Ia determinants coded by the I-A, I-B, and I-J regions of the H-2 gene complex completely abrogates the protective capacity of nylon-wool-purified T lymphocytes against leukemic challenge. This suggests that the Ia antigen bearing T cells play an important role in tumor immunity.This publication has 21 references indexed in Scilit:
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