Significance of Hyperamylasaemia and Abdominal Pain in Diabetic Ketoacidosis
- 21 July 1973
- Vol. 3 (5872) , 128-131
- https://doi.org/10.1136/bmj.3.5872.128
Abstract
An analysis of 35 consecutive episodes of diabetic ketoacidosis confirmed the frequent high levels of serum amylase in this condition. Serum amylase was raised during 21 episodes (60%), and in six instances (17%) the peak level exceeded 1,000 Somogyi units per 100 ml. Hyperamylasaemia was more often found when the initial blood sugar exceeded 500 mg/100 ml, or when the onset of the episode had been relatively acute (less than 48 hours). There was no conclusive evidence in any patient to support a diagnosis of acute pancreatitis and other explanations for the hyperamylasaemia are discussed. Even grossly raised amylase levels were not associated with increased mortality or morbidity.Keywords
This publication has 12 references indexed in Scilit:
- Simplified Turbidimetric Assay for Lipase ActivityClinical Chemistry, 1971
- A Comparative Study of the Isoenzymes of Mammalian a-AmylaseEnzyme, 1971
- Macroamylasemia: Rapid Detection MethodClinical Chemistry, 1971
- A new and rapid method for the clinical determination of α-amylase activities in human serum and urine. optimal conditionsClinica Chimica Acta; International Journal of Clinical Chemistry, 1969
- Diabetic acidosis with acute pancreatitisBritish Journal of Surgery, 1961
- The plasma amylaseThe American Journal of Medicine, 1959
- Acute PancreatitisBMJ, 1959
- Amylase distribution in extrapancreatic, extrasalivary tissuesArchives of Biochemistry and Biophysics, 1958
- Acute Pancreatitis ComplicatingA.M.A. Archives of Internal Medicine, 1956
- ACUTE METHYL ALCOHOL POISONING: A REVIEW BASED ON EXPERIENCES IN AN OUTBREAK OF 323 CASESMedicine, 1953