AUTORADIOGRAPHIC STUDIES OF THE DISTRIBUTION OF 1-AMINOCYCLOPENTANE CARBOXYLIC ACID IN NORMAL AND CANCEROUS MICE
- 1 August 1962
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Biochemistry and Physiology
- Vol. 40 (8) , 1111-1114
- https://doi.org/10.1139/o62-124
Abstract
Normal and cancerous mice were injected with 1-aminocyclopentane C14-carboxylic acid and the distribution of the drug in the animals was studied by autoradiography. In normal mice, the amino acid is concentrated selectively by the pancreas and the bone marrow. In cancerous mice (Ehrlich ascites tumor and sarcoma-180), the tumor cells also intensively accumulate the amino acid.Keywords
This publication has 2 references indexed in Scilit:
- Cycloaliphatic Amino Acids in Cancer ChemotherspyJournal of Medicinal Chemistry, 1961
- The tumour growth inhibitory activity of 1-amino-cyclopentane-1-carboxylic acid and related peptidesBiochemical Pharmacology, 1959