Biochemical Evidence on the Role of Gangliosides in Nerve-Endings
- 1 January 1976
- book chapter
- Published by Springer Nature
- Vol. 71, 137-150
- https://doi.org/10.1007/978-1-4614-4614-9_9
Abstract
The nervous system, compared to other tissues, is characterized by high ganglioside levels, most particularly of the tri- and tetra-sialogangliosides (WIEGANDT, 1968). This simple fact has led to many suggestions that gangliosides must have a neuro-specific function to match their neurospecific concentration and pattern. The purpose of this article is to examine the evidence that the gangliosides have a role in synaptic function, since it is at the synaptic region that the gangliosides seem to be concentrated.Keywords
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