EFFECT OF INTRAVENOUS FLUIDS ON DEHYDRATED PATIENTS AND ON NORMAL SUBJECTS

Abstract
Dehydration is frequently encountered in both medical and surgical patients. Whether dehydration is the result of vomiting, diarrhea, inability to swallow or electrolyte derangement such as occurs in diabetic acidosis,1the intravenous administration of fluids is the mode of therapy usually relied on to restore the normal state of hydration and electrolyte balance. Indeed, so routinely and with such gratifying results are intravenous fluids used for these patients that the physician seldom pauses to consider the exact effect of his therapy on the cardiovascular system. Previous reports in the literature have dealt with the effect of intravenous infusions on pulse rate, blood pressure, blood volume, venous pressure, velocity of blood flow and the electrocardiogram.2Altschule and Gilligan3have also reported the changes in cardiac output in normal men. However, no workers, so far as we are aware, have studied the effect of intravenous fluids on cardiac output

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