Fatty acid control of growth of human cervical and endometrial cancer cells
Open Access
- 31 March 1990
- journal article
- research article
- Published by Springer Nature in British Journal of Cancer
- Vol. 61 (4) , 500-503
- https://doi.org/10.1038/bjc.1990.113
Abstract
Stearic acid and iodo-stearic acid inhibited cell growth in a cervical cancer cell line (HOG-1) in a dose-related manner, with a half maximal effect at 50 .mu.m stearic acid. Addition of oleic acid abrogated the effect of stearic acid. EGF-stimulated DNA synthesis and growth of HOG-1 cells was inhibited in the presence of stearic acid without any apparent effect on EGF receptor or affinity.Keywords
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