Lupin alkaloids from teratogenic and nonteratogenic lupins. IV. Concentration of total alkaloids, individual major alkaloids, and the teratogen anagyrine as a function of plant part and stage of growth and their relationship to crooked calf disease
- 30 June 1976
- journal article
- research article
- Published by Taylor & Francis in Journal of Toxicology and Environmental Health
- Vol. 1 (6) , 899-908
- https://doi.org/10.1080/15287397609529392
Abstract
The concentrations of total alkaloids and individual major alkaloids including the teratogen anagyrine were measured in various plant parts of teratogenic lupins as the plants matured. All alkaloids including anagyrine were high in concentration in above‐ground parts early in growth and decreased as plants matured, except for an increase in mature, intact seeds. Seeds were highest, followed by early growth leaves and stems. Roots were lowest with mature leaves and stems only slightly higher. Pregnant cows have the greatest risk of giving birth to calves with crooked calf disease when the concentration of the teratogen anagyrine is highest and the cows are in the susceptible 40–75 day gestation period when ingesting the plant.This publication has 5 references indexed in Scilit:
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- Lupin alkaloids from teratogenic and nonteratogenic lupins. II. Identification of the major alkaloids by tandem gas chromatography‐mass spectrometry in plants producing crooked calf diseaseTeratology, 1973
- Lupin alkaloids from teratogenic and nonteratogenic lupins. I. Correlation of crooked calf disease incidence with alkaloid distribution determined by gas chromatographyTeratology, 1973
- Crooked calf syndrome, a plant-induced congenital deformityReproduction in Domestic Animals, 1967
- LUPINE A CAUSE OF CROOKED CALF DISEASE1967