Discovery of subtype-selective metabotropic glutamate receptor ligands using functional HTS assays
- 1 June 2000
- journal article
- review article
- Published by Elsevier in Drug Discovery Today
- Vol. 5, 20-26
- https://doi.org/10.1016/s1359-6446(00)01499-9
Abstract
No abstract availableKeywords
This publication has 39 references indexed in Scilit:
- 2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonistPublished by Elsevier ,1999
- [2] Fluorescence techniques for measuring ion channel activityPublished by Elsevier ,1999
- Metabotropic glutamate receptors: electrophysiological properties and role in plasticityBrain Research Reviews, 1999
- Cloning and stable expression of the mGluR1b subtype of human metabotropic receptors and pharmacological comparison with the mGluR5a subtypeNeuropharmacology, 1997
- PHARMACOLOGY AND FUNCTIONS OF METABOTROPIC GLUTAMATE RECEPTORSAnnual Review of Pharmacology and Toxicology, 1997
- High Throughput 96-Well Plate Assay for Receptor-Mediated Phosphatidylinositol TurnoverSLAS Discovery, 1997
- Growth factor upregulation of a phosphoinositide-coupled metabotropic glutamate receptor in cortical astrocytesJournal of Neuroscience, 1995
- Molecular and functional characterization of recombinant human metabotropic glutamate receptor subtype 5Neuropharmacology, 1995
- The metabotropic glutamate receptors: Structure and functionsNeuropharmacology, 1995
- Receptor subtypes or species homologues: relevance to drug discoveryTrends in Pharmacological Sciences, 1993