Radionuclide Imaging Metabolic Activity of Brown Adipose Tissue in a Patient with Pheochromocytoma
- 1 November 2004
- journal article
- case report
- Published by Georg Thieme Verlag KG in Experimental and Clinical Endocrinology & Diabetes
- Vol. 112 (10) , 601-603
- https://doi.org/10.1055/s-2004-830407
Abstract
We describe a patient with extra-adrenal pheochromocytoma and high plasma norepinephrine levels. Radionuclide images of this patient obtained using 18F-fluorodeoxyglucose and 123I-metaiodobenzylguanidine revealed bilateral tracer accumulation in the shoulder and lower neck. The regions of radiotracer uptake corresponded to the location of human brown adipose tissue (BAT). Excessive sympathetic stimulation by high circulating catecholamine concentrations augmented the metabolic activity and tracer uptake in the BAT. This study showed that radionuclide imaging can noninvasively visualize human BAT in terms of metabolic and functional activity.Keywords
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