Coexisting Metastatic Choriocarcinoma and Normal Pregnancy

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Abstract
A report of widely metastatic choriocarcinoma coexisting with a normal intrauterine pregnancy is presented. A primary lesion was not demonstrated in the placenta, and the possible origins of the neoplasm are discussed. Following 2 emergency abdominal surgical procedures, intensive chemotherapy consisting of a combination of metho-trexate, vinblastine, and actinomycin D was administered between 30 and 36 weeks of gestation. The infant was delivered vaginally at 37 weeks and exhibited slight transitory encephalopathy, mild anemia, and urinary tract infection, all of which cleared during the neonatal period. Maternal remission was achieved and has persisted.

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