Eine Apparatur zur Messung motorischer Funktionsstörungen bei Ratten
- 1 January 1976
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 50 (3) , 281-283
- https://doi.org/10.1007/bf00426845
Abstract
A runway apparatus for rats has been developed for measuring motor incoordination and running time. Animals were trained to run along an elevated narrow pathway. Frequency and severity of slipping off and running time were automatically counted. Rats were given diazepam, phenobarbital or chlorpromazine orally and tested 1 h later. Diazepam, 8–64 mg/kg p.o., caused slipping off in a dose-dependent manner. Phenobarbital had a similar effect with 64 mg/kg p.o. Chloropromazine, 32 and 64 mg/kg p.o., caused other signs of motor deficit.Keywords
This publication has 2 references indexed in Scilit:
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- Zur Testung depressiv auf das Zentralnervensystem wirkender PharmakaPsychopharmacology, 1960