Reproducibility of histamine challenge tests in asthmatic children.
Open Access
- 1 April 1983
- Vol. 38 (4) , 258-260
- https://doi.org/10.1136/thx.38.4.258
Abstract
The measurement of bronchial reactivity by histamine challenge testing is of increasing clinical importance in paediatrics. By means of a simple tidal breathing technique for the measurement of histamine sensitivity (expressed as PC20--the concentration of histamine which produces a 20% fall in peak flow rate) in childhood asthma, the reproducibility of pairs of tests was estimated over one hour and 24-hour intervals in 22 children. Under carefully controlled conditions the 95% confidence limits of PC20 were 0.8-1.25 X baseline PC20 after one hour and 0.36-2.8 X baseline PC20 after 24 hours.This publication has 12 references indexed in Scilit:
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