Isolation and structure of the bacterial sex pheromone, cAD1, that induces plasmid transfer in Streptococcus faecalis
- 3 December 1984
- journal article
- Published by Wiley in FEBS Letters
- Vol. 178 (1) , 97-100
- https://doi.org/10.1016/0014-5793(84)81248-x
Abstract
The Streptococcus faecalis sex pheromone cAD1, which is involved in the conjugative transfer of the hemolysin plasmid pAD1, has been isolated and its structure determined. Its M r is 818 and its amino acid sequence is H-Leu-Phe-Ser-Leu-Val-Leu-Ala-Gly-OH. A replicate of the pheromone synthesized by the liquid phase method showed the same biological activity and Chromatographie behavior as the isolated cAD1. Pheromone activity was detectable at a concentration of ~ 5 × 10−11 M.Keywords
This publication has 14 references indexed in Scilit:
- Plasmid Content of Streptococcus faecalis Strain 39-5 and Identification of a Pheromone (cPD1)-induced Surface AntigenMicrobiology, 1983
- New detection and separation method for amino acids by high-performance liquid chromatographyJournal of Chromatography A, 1981
- Plasmids, drug resistance, and gene transfer in the genus Streptococcus.Microbiological Reviews, 1981
- Plasmid transfer in Streptococcus faecalis: Production of multiple sex pheromones by recipientsPlasmid, 1979
- Induced cell aggregation and mating in Streptococcus faecalis: evidence for a bacterial sex pheromone.Proceedings of the National Academy of Sciences, 1978
- The use of N-hydroxy-5-norbornene-2,3-dicarboximide acitive esters in peptide synthesis.CHEMICAL & PHARMACEUTICAL BULLETIN, 1974
- Use of Anhydrous Hydrogen Fluoride in Peptide Synthesis. I. Behavior of Various Protective Groups in Anhydrous Hydrogen FluorideBulletin of the Chemical Society of Japan, 1967