IMAGING OF THE HUMAN-HEART AFTER ADMINISTRATION OF L-(N-13)GLUTAMATE

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  • 1 January 1980
    • journal article
    • research article
    • Vol. 21  (10) , 988-991
Abstract
In normal volunteers and cancer patients, studies using L-(13N) glutamate as an imaging agent showed localization of 13N activity in the heart. Other organs that were well visualized include the liver, pancreas and salivary glands. In 10 subjects the average myocardial uptake after i.v. injection of labeled glutamate was (5.7 .+-. 0.39)% (SEM, standard error of mean) of injected dose, as determined by a quantitative scanning system. The concentration of 13N activity in the human heart could not be predicted from previous studies involving myocardial uptake in dogs and rodents after administration of L-(13N)glutamate.

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