Pulmonary capillary pressure and filtration coefficient in the isolated perfused lung

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Abstract
An "isogravimetric" method was used to estimate the pulmonary capillary pressure, to determine the arterial and venous resistances in the isolated perfused lobe of a dog''s lung, and to determine its filtration coefficient. The average pulmonary capillary pressure found in 51 experiments was 7.0 + 1.4 mm Hg SD. The average pulmonary arterial and venous resistances were 0.018 and 0.014 mm Hg/ml/min; respectively. The relative distribution of these resistances in relation to total resistance of the lobe was approximately 56% arterial and 44% venous. The filtration coefficient for the pulmonary capillary membrane was 0.070 [plus or minus] 0.010 SD g/mm Hg/min./100 g of tissue.