SERUM FSH, LH AND PROLACTIN IN NORMAL MALES AND PATIENTS WITH PROSTATIC DISEASES

Abstract
Serum FSH [follicle stimulating hormone], LH [luteinizing hormone] and prolactin were measured in 58 normal males between 30-80 yr of age. At the same time, similar estimations were performed on samples taken from 232 patients with benign prostatic hypertrophy (BPH) and 26 patients with prostatic carcinoma. The 3 groups were compared with respect to age. Significant rises related to age occurred in the serum levels of FSH, LH and prolactin in normal men after the 6th decade. The patient groups did not differ significantly from each other, or from the normal age-matched population in respect to prolactin and FSH levels. Serum LH in both the carcinoma and BPH patient groups differed significantly from the controls, and remained at the level associated with younger normal males. Testosterone metabolites from the prostate may exert a negative feedback on pituitary LH secretion.