Synthesis and properties of 7-hydroxymethotrexate polyglutamyl derivatives in Ehrlich ascites tumor cells in vitro.
Open Access
- 1 April 1984
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 259 (8) , 5066-5072
- https://doi.org/10.1016/s0021-9258(17)42956-5
Abstract
No abstract availableThis publication has 37 references indexed in Scilit:
- Synthesis, Retention, and Biological Activity of Methotrexate Polyglutamates in Cultured Human Breast Cancer CellsJournal of Clinical Investigation, 1982
- DDMP (2,4-diamino-5-(3′,4′-dichlorophenyl)-methylpyrimidine)Cancer Treatment Reviews, 1980
- The role of 7-hydroxymethotrexate during methotrexate anti-cancer therapyCancer Letters, 1980
- Polyglutamate derivatives of folic acid coenzymes and methotrexateLife Sciences, 1980
- A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnalytical Biochemistry, 1976
- 7-Hydroxymethotrexate as a urinary metabolite in human subjects and rhesus monkeys receiving high dose methotrexate.Journal of Clinical Investigation, 1976
- Stoichiometric inhibition of mammalian dihydrofolate reductase by the γ-glutamyl metabolite of methotrexate, 4-amino-4-deoxy-N10-methylpteroylglutamyl-γ-glutamateBiochemical and Biophysical Research Communications, 1975
- Methotrexate Hepatotoxicity in Psoriasis--Comparison of Different Dose RegimensBMJ, 1972
- Metabolite of 4-Amino-4-deoxy-N10-methylpteroylglutamic Acid (Methotrexate)Journal of Pharmaceutical Sciences, 1967
- Enzymic oxidation of methotrexate and aminopterinLife Sciences, 1964