Effects of Source, Sex and Gnotobiosis on Susceptibility of Adult Mice to Coxsackie B-l Virus
- 1 August 1964
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 116 (4) , 1007-1008
- https://doi.org/10.3181/00379727-116-29433
Abstract
Summary A distinct difference exists in the susceptibility of different strains of conventional 18-20 g Swiss albino mice to infection with the lethal GP strain of Coxsackie B-1 virus. The sex of the animal is not a determinant with regard to susceptibility to the infection. Germ-free Swiss albino mice (Charles River CD-1 strain) were significantly less susceptible to the infection with Coxsackie B-1 virus (GP strain) than were their conventional counterparts.Keywords
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