Peak Detection Logic Systems of Gas Chromatographic Integrators

Publisher Website
Google Scholar
Abstract
Integration of gas chromatographic peaks requires that peak integration limits be defined. Integration must be performed over the peak envelope and constrained by the intersection of the base line with the peak. A variety of detection schemes have been implemented to determine a peak from a base line. Some of these schemes have included provision for measuring base line to correct peak integrals for base line drift. The simplest systems monitor the chromatographic signal until its absolute amplitude reaches a predetermined value, at which time integration begins. More sophisticated equipment differentiates the signal. The positive half of the derivative is used to detect peak onset while the negative half is used to detect peak end. Still further refinement is achieved in some systems by calculation of the second (and sometimes third) derivative. These higher order derivatives contain base line deviation information, useful for more accurate base line extrapolation under a peak. This paper reviews some of the hardware and the computer software which has been used to detect peaks, and to make base line corrections.

This publication has 0 references indexed in Scilit: