The buccal absorption of some barbiturates

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Abstract
The buccal absorptions of five barbiturates have been determined over the pH range 3 to 9. The absorptions increased as the pH decreased until pH 5.5 when they remained constant. No correlation between the absorptions and chloroform–0.1n HCl partition coefficients was apparent, indicating that the adsorptive power of the buffer-buccal membrane interface may represent more exactly the real affinity of the membrane for barbiturates than do partition coefficients with chloroform.