Abstract
Postoperative pneumonia in the surgical patient may occur from atelectasis and inadequate postoperative TV, from ventilator-associated pathophysiology and from aspiration. Each process ultimately elicits the proinflammatory responses from the lung in the effort to eradicate the infectious pathogens. Postoperative pneumonia is best prevented by maintaining a clear understanding of the biologic basis for infection in the lung. Therapy requires aggressive tracheobronchial drainage strategies and antibiotic therapy directed toward the pathogens that are producing the pulmonary inflammatory response.

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