ULTRASTRUCTURE OF ALZHEIMER TYPE II GLIA IN HEPATOCEREBRAL DISEASE
- 1 March 1981
- journal article
- research article
- Published by Wiley in Neuropathology and Applied Neurobiology
- Vol. 7 (2) , 97-102
- https://doi.org/10.1111/j.1365-2990.1981.tb00079.x
Abstract
In a case of hepatocerebral disease of Inose type the astrocytes, corresponding to Alzheimer type II glia, had swollen cytoplasm containing glycogen granules and focal aggregates of lipofuscin granules. Their nuclei contained bodies of simple and of complex types as well as conglomerates of glycogen granules without any capsules. The nuclear bodies of simple type were also observed in the nuclei of endothelial cells. It is concluded that these changes in the appearance of Alzheimer type II glia suggest reactive and defensive changes in the brain against ammonium ions, rather than being merely degenerative in nature.This publication has 9 references indexed in Scilit:
- Intranuclear inclusions in a case of Creutzfeldt-Jakob diseaseActa Neuropathologica, 1975
- Ultrastructural responses of the astrocytes to portocaval anastomosis in the ratJournal of the Neurological Sciences, 1973
- Nuclear bodies in human thymusJournal of Ultrastructure Research, 1969
- Electron microscopy in human hepatic encephalopathyActa Neuropathologica, 1968
- Subacute sclerosing panencephalitisNeurology, 1968
- New aspect of hepatic nuclear glycogenosis in diabetesJournal of Clinical Pathology, 1968
- Ultrastructural variations of nuclear bodies in human diseasesJournal of Ultrastructure Research, 1967
- Nuclear Inclusions in Malignant GliomasArchives of Neurology, 1965
- Hepatocerebral Degeneration, a Special TypeJournal of Neuropathology and Experimental Neurology, 1952