Comparison of 1,800 Laparoscopic and Open Partial Nephrectomies for Single Renal Tumors

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The incidence of RCC has increased by 2.3% to 4.3% each year since the 1970s, resulting in more than 35,000 new diagnoses and more than 12,000 deaths annually in the United States alone.1 x 1 Chow, W.H., Devesa, S.S., Warren, J.L., and Fraumeni, J.F. Jr. Rising incidence of renal cell cancer in the United States. JAMA. 1999; 281: 1628 Crossref | PubMed | Scopus (1193) | Google Scholar See all References , 2 x 2 Jemal, A., Murray, T., Ward, E., Samuels, A., Tiwari, R.C., Ghafoor, A. et al. Cancer statistics, 2005. CA Cancer J Clin. 2005; 55: 10 Crossref | PubMed | Scopus (5227) | Google Scholar See all References More than 60% of renal tumors are now detected incidentally.3 x 3 Janzen, N.K., Kim, H.L., Figlin, R.A., and Belldegrun, A.S. Surveillance after radical or partial nephrectomy for localized renal cell carcinoma and management of recurrent disease. Urol Clin North Am. 2003; 30: 843 Abstract | Full Text | Full Text PDF | PubMed | Scopus (455) | Google Scholar See all References Incidentally detected renal masses are smaller and less likely to metastasize.4 x 4 Patard, J.J., Dorey, F.J., Cindolo, L., Ficarra, V., De La Taille, A., Tostain, J. et al. Symptoms as well as tumor size provide prognostic information on patients with localized renal tumors. J Urol. 2004; 172: 2167 Abstract | Full Text | Full Text PDF | PubMed | Scopus (45) | Google Scholar See all References OPN has been established to provide better preservation of renal function and equivalent oncological outcomes compared with radical nephrectomy in select patients.5 x 5 Lee, C.T., Katz, J., Shi, W., Thaler, H.T., Reuter, V.E., and Russo, P. Surgical management of renal tumors 4 cm. or less in a contemporary cohort. J Urol. 2000; 163: 730 Abstract | Full Text | Full Text PDF | PubMed | Scopus (528) | Google Scholar See all References , 6 x 6 Lau, W.K., Blute, M.L., Weaver, A.L., Torres, V.E., and Zincke, H. Matched comparison of radical nephrectomy vs nephron-sparing surgery in patients with unilateral renal cell carcinoma and a normal contralateral kidney. Mayo Clin Proc. 2000; 75: 1236 Abstract | Full Text | Full Text PDF | PubMed | Scopus (588) | Google Scholar See all References , 7 x 7 McKiernan, J., Simmons, R., Katz, J., and Russo, P. Natural history of chronic renal insufficiency after partial and radical nephrectomy. Urology. 2002; 59: 816 Abstract | Full Text | Full Text PDF | PubMed | Scopus (416) | Google Scholar See all References