Activation and Inhibition of the Mg-Ca-ATPase from E. coli by Mg²⁺ and Ca²⁺

Open Access

1 June 1975

journal article
research article
Published by Walter de Gruyter GmbH in Zeitschrift für Naturforschung C

Vol. 30 (5-6) , 412-416
https://doi.org/10.1515/znc-1975-5-618

Abstract

MgATP of CaATP is the substrate of the Mg-Ca-ATPase. At low Mg2+- or Ca2+-concentrations the ATPase is activated by Mg2+ or Ca2+, the activator being essential for activity. At higher Mg2+- or Ca2+-concentrations the Mg-Ca-ATPase is inhibited competitively. Thus the real Km is smaller than reported in the literature. H+ competes with Mg2+ or Ca2+ for the metal binding sites.

Keywords

MG-CA-ATPASE
E. COLI
ACTIVATION
INHIBITION

Activation and Inhibition of the Mg-Ca-ATPase from E. coli by Mg2+ and Ca2+

Abstract

Keywords

Activation and Inhibition of the Mg-Ca-ATPase from E. coli by Mg²⁺ and Ca²⁺