The use of competitive inhibition of substrate-binding to cytochrome P450 in the determination of spectral dissociation constants for substrates with multiple types of binding, as illustrated with 1-butanol
- 1 January 1979
- journal article
- Published by Elsevier in Biochemical Pharmacology
- Vol. 28 (1) , 37-41
- https://doi.org/10.1016/0006-2952(79)90267-3
Abstract
No abstract availableKeywords
This publication has 19 references indexed in Scilit:
- The relation between the sex-dependency of type I binding of ethylmorphine and the 1-butanol-induced spectral change in mouse liver microsomesBiochemical Pharmacology, 1979
- The development of sex differences in the demethylation of ethylmorphine and in its interaction with components of the hepatic microsomal cytochrome P450 system in miceBiochemical Pharmacology, 1978
- Sex- and strain-dependent hepatic microsomal ethylmorphine N-demethylation in mice: The roles of type I binding and NADPH-cytochrome P-450 reductaseChemico-Biological Interactions, 1977
- Heterogeneity of cytochrome P‐450 in rat liver microsomes: Selective interaction of metyrapone and SKF 525‐A with different fractions of microsomal cytochrome P‐450FEBS Letters, 1975
- The interaction of variousN-substituted amphetamines with cytochromeP-450 of rabbit liver microsomesFEBS Letters, 1973
- The effect of castration and testosterone on some components of the microsomal drug metabolising enzyme system in miceFEBS Letters, 1972
- A study of the modified type II spectral change produced by the interaction of agroclavine with cytochrome P-450Biochimica et Biophysica Acta (BBA) - General Subjects, 1972
- Spectral Studies on the Interaction of Imipramine and some of its Oxidized Metabolites with Rat Liver MicrosomesXenobiotica, 1971
- Nature of the type I and II spectral changes in liver microsomesBiochemistry, 1970
- The determination of enzyme inhibitor constantsBiochemical Journal, 1953