Retinal Toxicity Study of Intravitreal Cyclosporin
- 1 March 1986
- journal article
- Published by SLACK, Inc. in Ophthalmic Surgery, Lasers and Imaging Retina
- Vol. 17 (3) , 155-156
- https://doi.org/10.3928/1542-8877-19860301-06
Abstract
We investigated the toxicity of intravitreal cyclosporin in the rabbit. Histologic retinal changes were found with intravitreal injections of 200 micrograms. No histologic or electroretinographic changes were observed with doses of 100 micrograms or less. This nontoxic dose is projected to be at least 77 times the amount needed to be effective.Keywords
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