The First Structural and Mechanistic Insights for Class D β-Lactamases: Evidence for a Novel Catalytic Process for Turnover of β-Lactam Antibiotics
- 1 June 2000
- journal article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 122 (25) , 6132-6133
- https://doi.org/10.1021/ja0013881
Abstract
No abstract availableThis publication has 10 references indexed in Scilit:
- Hydrogen Bonding and Attenuation of the Rate of Enzymic CatalysisJournal of the American Chemical Society, 1998
- Molecular Characterization of OXA-20, a Novel Class D β-Lactamase, and Its Integron from Pseudomonas aeruginosaAntimicrobial Agents and Chemotherapy, 1998
- The mechanism of catalysis and the inhibition of the Bacillus cereus zinc-dependent β-lactamaseBiochemical Journal, 1998
- Nuances of Mechanisms and Their Implications for Evolution of the Versatile β-Lactamase Activity: From Biosynthetic Enzymes to Drug Resistance FactorsJournal of the American Chemical Society, 1997
- Nomenclature of TEM beta-lactamasesJournal of Antimicrobial Chemotherapy, 1997
- Crystal Structure of 6α-(Hydroxymethyl)penicillanate Complexed to the TEM-1 β-Lactamase from Escherichia coli: Evidence on the Mechanism of Action of a Novel Inhibitor Designed by a Computer-Aided ProcessJournal of the American Chemical Society, 1996
- Design, Synthesis, and Evaluation of a Potent Mechanism-Based Inhibitor for the TEM .beta.-Lactamase with Implications for the Enzyme MechanismJournal of the American Chemical Society, 1995
- The Role of Tyrosine 150 in Catalysis of .beta.-Lactam Hydrolysis by AmpC .beta.-Lactamase from Escherichia coli Investigated by Site-Directed MutagenesisBiochemistry, 1994
- Evolutionary perspectives on multiresistance beta-lactamase transposonsJournal of Bacteriology, 1989
- Bacterial Resistance to β-Lactam Antibiotics: Crystal Structure of β-Lactamase from Staphylococcus aureus PC1 at 2.5 Å ResolutionScience, 1987