The PiGMaP consortium linkage map of the pig (Sus scrofa)
- 1 March 1995
- journal article
- research article
- Published by Springer Nature in Mammalian Genome
- Vol. 6 (3) , 157-175
- https://doi.org/10.1007/bf00293008
Abstract
A linkage map of the porcine genome has been developed by segregation analysis of 239 genetic markers. Eighty-one of these markers correspond to known genes. Linkage groups have been assigned to all 18 autosomes plus the X Chromosome (Chr). As 69 of the markers on the linkage map have also been mapped physically (by others), there is significant integration of linkage and physical map data. Six informative markers failed to show linkage to these maps. As in other species, the genetic map of the heterogametic sex (male) was significantly shorter (∼16.5 Morgans) than the genetic map of the homogametic sex (female) (∼21.5 Morgans). The sex-averaged genetic map of the pig was estimated to be ∼18 Morgans in length. Mapping information for 61 Type I loci (genes) enhances the contribution of the pig gene map to comparative gene mapping. Because the linkage map incorporates both highly polymorphic Type II loci, predominantly microsatellites, and Type I loci, it will be useful both for large experiments to map quantitative trait loci and for the subsequent isolation of trait genes following a comparative and candidate gene approach.Keywords
This publication has 144 references indexed in Scilit:
- Establishment of a Partially Informative Porcine Somatic Cell Hybrid Panel and Assignment of the Loci for Transition Protein 2 (TNP2) and Protamine 1 (PRM1) to Chromosome 3 and Polyubiquitin (UBC) to Chromosome 14Genomics, 1994
- The 1993–94 Généthon human genetic linkage mapNature Genetics, 1994
- Porcine (GT)n Sequences: Structure and Association with Dispersed and Tandem RepeatsGenomics, 1994
- Conserved Synteny between Pig Chromosome 8 and Human Chromosome 4 but Rearranged and Distorted Linkage MapsGenomics, 1993
- Assignment of 20 Microsatellite Markers to the Porcine Linkage MapGenomics, 1993
- Localization of Pig Na+,K+-ATPase α and β Subunit Genes to Chromosome 4 by Radioactive in Situ HybridizationGenomics, 1993
- The gene for dominant white color in the pig is closely linked to ALB and PDGFRA on chromosome 8Genomics, 1992
- Application of automated DNA sizing technology for genotyping microsatellite lociGenomics, 1992
- Localization on pig chromosome 6 of markers GPI, APOE, and ENO1, carried by human chromosomes 1 and 19, using in situ hybridizationCytogenetic and Genome Research, 1990
- THE ESTIMATION OF MAP DISTANCES FROM RECOMBINATION VALUESAnnals of Eugenics, 1943