The Deep Subcutaneous Administration of Concentrated Heparin

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Abstract
HEPARIN and Dicumarol are at present widely used in the prevention and treatment of thromboembolic diseases. The former has maintained its place, despite its expense, because of its predictability, rapidity of anticoagulant effect and lack of side reactions. Since heparin is excreted or neutralized by the body in a few hours, it must be given continuously or intermittently over relatively short periods of time. Only the parenteral route has been found effective. The standard method has been the constant intravenous drip of 200 to 300 mg. in 1.5 liters of intravenous solution daily, as reported by Murray.1 , 2 Intermittent intravenous heparin, . . .

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