Skin Toxic Effects of Polyethylene Glycol–Coated Liposomal Doxorubicin

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Abstract
DRUG DELIVERY systems hold considerable potential for oncology use by allowing preferential drug accumulation in target tissues and reducing toxic effects to healthy organs.1 Encapsulation of doxorubicin hydrochloride in liposomes is a successful application of this concept that is gaining widening acceptance for several indications, including acquired immunodeficiency syndrome–related Kaposi sarcoma2 and ovarian cancer.3