The Biogenesis of Ergot Alkaloids
- 1 May 1963
- journal article
- review article
- Published by Wiley in Angewandte Chemie International Edition in English
- Vol. 2 (5) , 243-247
- https://doi.org/10.1002/anie.196302431
Abstract
In this article the biogenesis of the ergoline ring in lysergic acid derivatives and the clavines is discussed. T·yptophan and mevalonic acid are the precursors. The N‐methyl group is supplied by formate or methionine. Concepts and results dealing with the manner in which the compounds are formed are discussed. Finally, the known biogenetic relationships among the ergot alkaloids are discussed in connection with their biogenesis.Keywords
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