Change in Cognitive Function Over Time in Very Low-Birth-Weight Infants

Abstract
Preterm birth results in significant neurodevelopmental disability during childhood.1,2 Depending on the birth weight of the children studied and the years in which they were born, the incidence of major disabilities ranges from 20% to almost 50% in the first several years of life.3-8 In addition, almost one fifth develop major cognitive disabilities by age 8 years,9,10 more than 50% are reported to require special assistance in the classroom, 20% are in special education, and 15% have repeated at least 1 grade in elementary school.10-13 However, recent reports suggest that two thirds of preterm infants require no special assistance in school at ages 14 to 15 years, almost three quarters graduate from high school, and more than 40% are enrolled in college programs. These data suggest change in cognitive function over time in those born preterm.14-18

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