EFFECT OF A ZINC-DEFICIENT DIET ON THE GROWTH OF AN IGM-SECRETING PLASMACYTOMA (TEPC-183)

  • 1 January 1980
    • journal article
    • research article
    • Vol. 65  (6) , 1271-1272
Abstract
A diet deficient in Zn resulted in a significant decrease in the number of inbred BALB/c female mice developing transplantable plasmacytoma TEPC-183 cells compared to pair-fed and ad lib-fed control mice. The size of the tumor relative to body weight was decreased in the Zn-deficient group. The uptake of [3H]thymidine into tumor cells did not differ between the groups; the incorporation of [3H]thymidine into tumor cells was significantly reduced in the animals maintained on a Zn-deficient diet.

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