Stimulation of residual insulin secretion by glibenclamide in insulin dependent diabetics
- 1 November 1980
- journal article
- research article
- Published by Oxford University Press (OUP) in Acta Endocrinologica
- Vol. 95 (3) , 372-375
- https://doi.org/10.1530/acta.0.0950372
Abstract
Residual insulin secretion, reflected by the presence of C-peptide in serum and urine, was demonstrated in 5 of 10 insulin-requiring diabetics of less than 10 yr duration tested. The C-peptide response, in the C-peptide secretors, showed a significant increase in both serum and urine after 4 wk treatment with 15 mg glibenclamide daily in addition of their usual insulin regime although no beneficial effects in metabolic control were detected. Glibenclamide might be a useful adjunct to insulin therapy in insulin-requiring diabetics who still secrete C-peptide.This publication has 5 references indexed in Scilit:
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