A RELATION BETWEEN NON-ESTERIFIED FATTY ACIDS IN PLASMA AND THE METABOLISM OF GLUCOSE

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Abstract
The concentration of non-esterified fatty acids (NEFA) in plasma increased with fasting, decreased after a mixed meal, oral glucose (50 g) or injected insulin (0.1 [mu]/kg), and rose markedly alter injection of epinephrine (0.5 mg). Corn oil, on the other hand, failed to cause any change even when enough was taken to produce gross lipemia. The fasting levels of NEFA were normal in 3 men with chronic elevation of total plasma lipids, neutral fat, cholesterol and phospholipids. A new method for determination of NEFA is described. It appears to be more rapid and sensitive than previous techniques.