CEREBROSPINAL-FLUID CYTOLOGY IN CANINE NEUROLOGIC DISEASE

  • 1 January 1977
    • journal article
    • research article
    • Vol. 38  (11) , 1827-1832
Abstract
Samples of CSF of 93 dogs with neurologic diseases were examined by cytomorphologic technique, and the changes in the CSF were correlated with histopathologic examinations of the CNS. CSF examination was a significant aid in obtaining a neurologic diagnosis and that good correlation exists between the CSF changes and the pathologic changes in the CNS. The CSF examination allowed making a diagnosis of encephalitis and differentiation between viral and other causes (although in mycotic infection the cell membrane preparation can be used to identify the cause directly), allowed making differentiation between congenital malformations and congenital degenerative disease and helped in identifying physical spinal cord damage, differentiating it from muscular, neurogenic or functional disorders clinically presented as spinal ataxia. The CSF cytologic examination could indicate the presence of hemorrhage in the CNS. There was not enough experience available in the diagnosis of brain tumors by means of CSF examination; however, in dogs with lymphosarcoma in the CNS, CSF cytologic changes could be diagnostic.

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