EFFECTS OF FAT-MOBILIZING EXTRACT FROM HUMAN URINE ON METABOLISM OF GLUCOSE IN RAT ADIPOSE TISSUE1

Abstract
Fat-mobilizing substance (PMS), a small peptide isolated from urine of carbohydrate deprived humans, alters carbohydrate metabolism in isolated epididymal adipose tissue in a pattern similar to that of epinephrine and preparations of ACTH and growth hormone. It is inferred that FMS primarily mobilizes fatty acids from adipose tissue by directly augmenting the lipolytic reaction.