Structure and putative origin of a plasmid from Staphylococcus hyicus that mediates chloramphenicol and streptomycin resistance
- 1 May 1994
- journal article
- Published by Oxford University Press (OUP) in Letters in Applied Microbiology
- Vol. 18 (5) , 281-284
- https://doi.org/10.1111/j.1472-765x.1994.tb00869.x
Abstract
The structure and functional organization of Staphylococcus hyicus plasmid pSCGp3EB that mediates chloramphenicol and streptomycin resistance (CmrSmr) is described and compared with another CmrSmr plasmid, pSCS12, from Staphylococcus sciuri. Both plasmids appeared to be formed by co-integrate formation between plasmids that very closely resemble the chloramphenicol resistance (Cmr) plasmid pC221 and the streptomycin resistance (Smr) plasmid pS194. In addition to the established recombination site B (RSB) in pC221 and pS194, another area suitable for recombination immediately downstream of the cat gene in pC221 and upstream of the str gene in pS194 has been identified. Co-integration at these sites would lead to the structures we have observed in the wild-type CmrSmr plasmids pSCGp3EB and pSCS12.Keywords
This publication has 12 references indexed in Scilit:
- Nucleotide sequence and structural relationships of a chloramphenicol acetyltransferase encoded by the plasmid pSCS6 from Staphylococcus aureusJournal of Applied Bacteriology, 1992
- A chloramphenicol-streptomycin-resistance plasmid from a clinical strain ofStaphylococcus sciuriand its structural relationships to other staphylococcal resistance plasmidsFEMS Microbiology Letters, 1991
- Nucleotide sequence and phylogeny of a chloramphenicol acetyltransferase encoded by the plasmid pSCS7 from Staphylococcus aureusAntimicrobial Agents and Chemotherapy, 1991
- Molecular cloning, purification, and properties of a plasmid-encoded chloramphenicol acetyltransferase from Staphylococcus haemolyticusAntimicrobial Agents and Chemotherapy, 1991
- Streptomycin and tetracycline resistance plasmids inStaphylococcus hyicusand other staphylococciJournal of Applied Bacteriology, 1991
- Common Antibiotic Resistance Plasmids in Staphylococcus aureus and Staphylococcus epidermidis from Human and Canine InfectionsZentralblatt für Bakteriologie, 1990
- Structural relationships among chloramphenicol-resistance plasmids of Staphylococcus aureusFEMS Microbiology Letters, 1988
- Nucleotide sequence of pS194, a streptomycin-resistance plasmid fromStaphylococcus aureusNucleic Acids Research, 1988
- Comparative sequence and functional analysis of pT181 and pC221, cognate plasmid replicons from Staphylococcus aureusMolecular Genetics and Genomics, 1985
- The toxic shock syndrome exotoxin structural gene is not detectably transmitted by a prophageNature, 1983