EFFECT OF AMINO-ACID RESTRICTED DIETS ON CLEARANCE OF I-125-LABELED POLYVINYL PYRROLIDONE IN MICE
- 1 January 1976
- journal article
- research article
- Vol. 23 (3) , 562-567
Abstract
Impaired overall phagocytic function, as measured by clearance of radio-labeled polyvinyl pyrrolidone from the blood (KPVP), was demonstrated in mice whose dietary intake of the essential amino acids phenylalanine and tryptophan was reduced to less than a quarter of that in a standard diet which supported optimal growth. This was associated with loss in weight of body, liver, spleen and thymus and an increase in the phagocytic index, .alpha.PVP.This publication has 10 references indexed in Scilit:
- Ion-exchange chromatography of the more basic amino acids of protein hydrolysates using stepwise changes of buffers containing borate ionsJournal of Chromatography A, 1975
- Relationship between macrophage clearance of PVP and affinity of anti-protein antibody response in inbred mouse strainsNature, 1975
- The effects of protein malnutrition on macrophage function and the amount and affinity of antibody response.1974
- Effects of protein insufficiency on immune responsivenessThe American Journal of Clinical Nutrition, 1974
- QUANTITATIVE EFFECTS OF NUTRITIONAL ESSENTIAL AMINO ACID DEFICIENCY UPON IMMUNE RESPONSES TO TUMORS IN MICEThe Journal of Experimental Medicine, 1973
- THYMOLYMPHATIC DEFICIENCY AND DEPRESSION OF CELL-MEDIATED IMMUNITY IN PROTEIN-CALORIE MALNUTRITIONThe Lancet, 1971
- Malnutrition with Early Treatment of PhenylketonuriaPediatric Research, 1970
- Phenylalanine deficiency syndromeThe Journal of Pediatrics, 1966
- The adrenal cortex and the response of the fixed macrophagic cell to chronic inanitionThe Anatomical Record, 1952